Samphire Neuroscience Avis 99

The Lutea has been game-changing for me. I struggle with complex chronic illness, and it's made a huge difference for me, from decreasing my vulvodynia and period pain, to reducing anxiety (so much so that I'm doing less therapy!), to increasing my focus and energy.

I'm very sensitive to medication, and am amazed by how effective Lutea is without side effects (other than minor tingling while using it, which I'd take over my symptoms any day!).

I used it during my egg freezing process, and it made a massive difference with that, too. My boyfriend and I both looked forward to when I'd use it each day. It significantly improved my energy and mood and reduced my pain, bloating, and headaches. It was like night and day during that process. I'm still using it 1-2 times a day now and couldn't recommend it more. Give it a try, you won't be disappointed!

Also, the staff have been incredibly responsive and supportive, too! Thank you!!!

I took my time to make the decision to purchase a headset. For a few months I researches the company and neuro stimulation. And I watched a webinar from the team explaining exactly how the technology worked (and asked my husband to watch along too!) and read the honest reviews from those who had experience. We made an informed decision together to try this and I'm so glad I did. I use the headset as part of my holistic management of PMDD which includes a low dose SSRI. I have been using the technology monthly for 7 months now and I can confirm that my bad days have reduced by at least 3 days so far from up to 2 weeks. I feel generally calmer and more myself in my luteal phase. Thank you for Em and Cat for all your help so far - I'm excited to hear more about this becoming an official treatment option!

I am almost through my first cycle using Lutea for PMDD and it’s already been life changing. I also have hEds, decompressed Chiari, ADHD and a few others but the PMDD has been the hardest to manage. So far-no blow out fights with my partner, no inescapable downward spirals, no SI and a large decrease in physical symptoms as well. I have tried all the pharmaceuticals with no improvement, I haven’t worked in years to focus solely on surviving my own body. I have been using antihistamines, supplements, staying active, eating clean, all the lifestyle changes that bring 1% relief with each change and the last 3 cycles before this felt like I wouldn’t make it to menopause as I’m only 36. This headband makes me feel like maybe I could be a functioning member of society before I turn 50 and I haven’t ever felt that way with everything else I have been doing. The only side effect is skin irritation and I could not be bothered to care because the mental relief in such a short amount of time is so substantial. I wander and read during the sessions to distract myself from the tingling so I’d call it mild discomfort. If you’ve tried everything without relief, try one last time with this 🫶

Samphire is an amazing woman-led company where everyone involved cares about what they do, and it shows. When I first bought my Lutea, I had some technical difficulties (thick hair) getting it to make contact, and after reaching out to the Samphire team, they gave me a ton of things to try, and even included videos to show easier ways for thick haired people to get their headbands to create contact more easily. They have always been insanely responsive and helpful. I also looooove the Samphire app and the way it allows for symptom tracking, medication tracking, and exporting data to share with providers (or just look at yourself) later on. It is incredible.

I'm on my fifth cycle of using Nettle and can honestly say it has made my luteal phase SO much easier. I was sceptical when I ordered the device and half-hoped it wouldn't work so I could get my money back – but it does work, and for me it has been well worth the money so far.

When it first arrived I found it difficult to get the sponges to connect. It still takes me two attempts to get the device fully connected, but it's pretty easy once you get used to it.

In terms of actual impact, before using Nettle I suffered from irritability, depression, fatigue and food cravings throughout luteal. During the first month of using Nettle, these symptoms were still present, but I began to see significant reductions in months 2 and 3. Now I only record 'mild' versions of these symptoms, and they occur much less frequently – around 1–4 days a month, versus 10 days a month prior to Nettle. I would estimate that my mental symptoms have decreased by 75%. This has made me feel more stable, has greatly benefited my relationships and has generally made it possible for me to go about life normally. It's honestly been amazing!

One caveat: I have a copper coil, so I experience bad cramps during my period. Nettle has reduced this pain, but only slightly – I would say it's more like a 25% reduction. I see the device has reduced pain for lots of other people, so I wonder if my situation is different because of the coil.

An interesting thing I've noticed is that when I use the device for 3 days of my period, it makes my period much lighter and shorter! I'm pretty happy with this side effect because the coil made my periods longer and heavier.

Overall, I would highly recommend Nettle to anyone suffering similar symptoms to me. I use it for two weeks every month, from around day 17 to around day 3. I'm so grateful to Samphire for paving the way in this under-researched area. I really hope they manage to get Nettle devices on the NHS to increase accessibility!

I have the Lutea. The app is immensely frustrating. I received the free subscription, I have a login and password but it keeps looping me back to pay for a subscription. Infuriating given that I just have these people close to $600 for something I cannot use because of a $60/month app. Hopefully it would be this difficult getting a refund!

Finally something that works. PMDD and endometriosis has been hell for years. Nettle has definitely reduced severity of symptoms. Worth it.

The headband is very easy to use and you can go about your day with it on. It's a little tickly at first but you get used to it. I've got pmdd and it's too early to tell if it's affecting my mood symptoms but I also have painful periods and cramps and I can't believe how much it's reduced my pain. Almost non existent pain now and the difference is crazy.

I have PMDD and my Lutea (Nettle) has been helping regulate my moods and energy levels.
Two months in and noticing a big difference.

This headband is a game changer. The example I’ll give, which most women with PMDD can relate to, is the feeling of being out of control of your emotions when tangled in a perceived conflict with your partner. These moments can get really intense, really fast, and one such situation presented itself in my first cycle using Lutea. I put the headband on and did a session when I was ruminating post conflict….and wow…within maybe 5 minutes I could see with such clarity what the miscommunication was, my role in it, and that it was in fact a storm in a teacup - that I was wasn’t seeing things clearly - and from that session I had regained my composure and agency to approach my partner with a whole heart and make things right. This was huge, and my first cycle was a lot less stressful than normal. I felt connected to my husband as a result. Mood regulation is so much better. I’m day 22 of the next cycle and started using the band yesterday at day 21 when things start to wobble. So far, so good. I love my Lutea!!

I work in women’s and mental health and using nettle has had the most significant impact on my PMDD related depression out of all other interventions I have tried. It is now something I recommend to clients. The team are always very responsive with any queries.

Nettle really helps me every month, and even knowing it's there as a tool for me makes a big difference. Sessions lift my mood and help me feel more in control of my mood and emotions. I've had it since September 25. The customer service is brilliant and I truly believe Samphire will be everywhere in 5 years, changing the game for even more women

Nettle helps me with my PMDS symptoms and makes everyday life much easier. Before Nettle, I was taking SSRIs, and on really bad days I would occasionally need a calming medication. Overall, I feel like I can control my emotions a little better now. There are fewer extremely bad days.
I use Nettle from ovulation until my period, so for quite a lot of days each month. At the beginning, I had an issue with the device, but the support team was very quick and truly excellent. I received a replacement right away and got immediate help.
Thank you for this wonderful invention! Nettle doesn’t cure my PMDS, but even the fact that it helps a little brings me so much relief. Thank you!

The Nettle has been life changing as someone with pcos and pmdd, and long term depression. It’s helped me to manage my mood and reduced my pain symptoms. It’s not like any other treatment I have experienced, with almost immediate lessening of my anxiety. After 9 months of use, I swear by it. It makes bad days much brighter and more manageable. I am so grateful to be able to experience this after years of struggling deeply. Thanks to the whole team. Great customer service too!

I've been using Nettle since May 2025, and it's given me real, felt relief from some of the psychological symptoms of my PMDD including anxiety, overwhelm, panic. The team is also amazingly responsive to questions/queries/feedback

Less crying, less snapping, just in general a more calm time before my periods. Between loosing weight and pre-menopause, my cycle has become notable longer than it used to be, and I'm so grateful that I don't have to spend that time waiting for my period and the calmer, more positive part of my cycle to begin. Or dreading the luteal phase, when my mood would start to dive.

I found Nettle on a Reddit page. Someone had mentioned a medical trial for PMDD and I was desperate. I was spending half of my month, every month unable to function as a human. I play several sports that require concentration to put it mildly, and I was actually refusing to do them for half of the month because it would end in screaming, tears or suicidal thoughts. I had really got to the end of my tether! I knew the doctors were going to be less than helpful, I didn't want to go down the SSRI or contraceptive route and had already been told a firm no on any permanent surgical solutions.

Nettle has somewhat changed my life! I was sceptical at first, the reviews almost seemed too good to be true but after 3 months (the first two believing it wasn't going to work and it was all a big lie) the changes have been nothing short of a miracle. I still have the odd day where I feel down or angry/irritable, but I am able to acknowledge this and walk away from the situation and start again. I now forget that I have booked competitions and leisure activities on my 'bad' days as they don't cause an issue.

Subsequently, after the medical trial I bought myself my own device and I haven't looked back since. If anyone is looking for an alternative that doesn't include years of being passed around doctor to doctor, just do it! With a money back trial too, what is there to lose in my opinion.

This is my first month using Nettle and already this cycle my luteal phase has been completely different. My PMDD Symptoms are practically nonexistent and hopefully it will help with endo pain as well. Will update to share results. I am amazed with Nettle!

I’ve been using Nettle since it launched and it’s made such a noticeable difference in my pms and pmdd symptoms. I used to have at least 2-3 days every month where I couldn’t function, either due to complete exhaustion, fatigue and anxiety or period pain in the first day of my cycle. With Nettle my body feels much more comfortable overall. My energy levels are sustained, I’m feeling more in control emotionally (not 100%) and the cramping is so much milder that I do not feel I need to take a pain killer anymore or lay down for a nap. Using Nettle allows me to feel more normal during my period and not to miss out on life.

The Nettle from Samphire has been a great addition to my PMDD protocol, I was one of the first batches and the customer service from the founder and her team was quick and efficient. As one of the first batches I got a lemon and it was dealt with quickly. I used it for months consistently and noticed a mood improvement which is such small statement but profound when PMDD disables your normal life. supporting a women led company is always a plus